We are in constant pursuit of breakthroughs that improve patients' lives. We drive innovation every day to make the world a more healthy place. This was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies achieve more, are more innovative, recruit and maintain the best talent, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that transform patients' lives—drives everything we do and shows our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has importance and embodies the value we aim to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We fulfill our purpose by finding the best science in the world, working with others in the healthcare system to improve access to our medicines, using digital technologies to enhance our drug discovery and development, as well as patient outcomes, and driving the conversation to campaign for pro-innovation/pro-patient policies. Every choice we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can flourish.