We are in constant pursuit of breakthroughs that transform patients' lives. We create innovations daily to make the world a healthier place. It was Charles Pfizer's initial vision, and it remains true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more innovative, draw and keep the best talent, and know how to maximize the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and reflects our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has meaning and embodies the value we work to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, working with others in the healthcare system to increase access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and driving the conversation to push for pro-innovation/pro-patient policies. Every choice we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.